Monday, September 7, 2015

key chains that leads to fat burning

HSL burns stored fat
perlipin guards stored fat
so have to:
1. get rid of perilipin to allow HSL to work
2. increase HSL

Key chains in fat burning:

adrenaline and/or glucagon > cAMP > PKA > reduce perilipin
higher fat diet > higher HSL > burns fats faster (assuming perilipin is gone to allow access to stored fat)

-First, perilipin is the shield that keeps fat cells from being broken down (by HSL). To burn stored fat you have to get rid of perilipin otherwise HSL cannot access fat.

-So the question is, how to you get rid of perilipin? Through activating cAMP which triggers PKA (protein kinase A). PKA phosphorylizes perilipin i.e. gets rid of it, which is the goal.

-So then how do you trigger PKA? This is the big question. Best answers now: through triggering the hormones glucagon and adrenaline (epinephrine)

-So then how do you trigger glucagon and epinephrine?

-Trigger glucagon by eating protein

-Trigger adrenaline by exercising at higher intensities

http://www.ncbi.nlm.nih.gov/books/NBK22429/

"glucagon / hsl axis" is really the [low perilipin] / hsl axis
http://www.unleashyourthin.com/eat-this-to-turn-on-your-fat-burning-switch/

1 comment:

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