Spending way too much time sitting is a serious health hazard, regardless of how much much you exercise when not sitting. Scientists suggest "interrupting" sitting by walking around periodically, standing while talking on the phone or to others, etc.
Experts: Sitting Too Much Could Be Deadly
http://www.cbsnews.com/stories/2010/01/20/health/healthy_living/main6119907.shtml
Your Health: Too much sitting puts the body on idle
http://www.usatoday.com/news/health/painter/2010-02-01-yourhealth01_ST_N.htm
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