Glucosepane: the key to future efforts to break up sticky AGE molecules

AGE or Advanced Glycation End Products, the sticky particles that accumulate in our bodies as a result of excess sugar, are thought to be behind a myriad of diseases and complications from heart disease to diabetes complications.

Now it is known that one AGE in particular, glucosepane, is the main AGE found in humans.

"Glucosepane is present in human tissues at levels 10 to 1000 times higher than any other cross-linking AGE, and is currently considered to be the most important cross-linking AGE."

The problem is that AGEs are difficult to remove because they are cross-linked to each other. Hence researchers are now seeking ways to break up the cross links in glucosepane.

When they do find a solution, this will be a massive breakthrough that could reverse heart disease and diabetes complications.

Iron overload/Hemochromatosis: wrecks the body but easy to fix

Iron overload/Hemochromatosis: wrecks the body but easy to fixProblem: Iron overload/HemochromotosisI have the gene for hemochromatosis which means I absorb way too much iron each time I eat iron-rich foods like red meat. This excess iron floating around in the bloodstream wreaks havoc on the body: it nicks arteries in the bloodstream leading to heart disease and also is linked to cancer along with other problems. Also, over time excess iron rusts i.e. oxidizes, which is linked to cancer, and also overloads the liver where iron is stored. Some people have extreme iron overload in which their liver is literally "full" of iron and can't hold any more so that any iron they eat just swirls around and around in the blood stream.

This is a problem that is easy to fix thanks to new discoveries. It used to be that people had to give blood in order to reduce their iron, often giving blood every month to keep from having iron overload.

Solution: IP6
But now a supplement called IP6 easily and painlessly reduces iron. Actually, the active ingredient in IP6 is phytic acid which is very commonly found in grains like brown rice, wheat, even chocolate. But with IP6 you can get the phytic acid without having to eat all the grains, and you can easily get a lot of it to quickly bring down your iron.

Improved chart of purine levels in foods for gout

This guy subtracted out certain types of purines that he says do not affect gout from the totals.

Improved chart of purine levels in foods for gout
http://www.goutpal.com/gout-diet/purine-rich-foods/

Walking benefits not to be confused with low-intensity cardio

Walking has tremendous benefits but is not to be confused with low-intensity cardio. They are very different.

Key point: If your body isn't designed for low-intensity cardio (long runs, marathons, endurance cycling, etc.), you should not simply throw out the idea of walking as if walking is just another form of endurance cardio. It is not.

Walking is walking. It is not really "cardio" at all, it's just walking--and that's OK. True "cardio" is exercise that raises your heart rate significantly. Walking does not. (unless you are "power walking" which is a different topic). Low-intensity cardio, on the other hand, is basically the long, slow running of the type that marathon runners do, what we might call slow jogging.

So yes, walking is low-intensity, but no, it is not cardio.

Walking is vital despite not being cardio
Walking has tremendous benefits but they are not really due to the raising of heart rate. The benefits of walking include a wide range:
-simply not being sedentary i.e. sitting/lying
-triggers anti-inflammatory shifts in the body
-triggers the body's "motion sensors" to sense it is on the move and hence needs to shed weight
-circulation
-highest
and the list goes on -- see Top 10 benefits of walking
http://www.sharecare.com/health/walking/article/walking-benefits

Low-intensity cardio results in problems that walking does not
Low intensity cardio...
-depletes glycogen (sugar) stores fast; walking does not
-puts a pounding on joints and feet; walking does not
-is not really an option for athletes with mostly fast-twitch muscle; they are just not built for it and their muscles will hit a wall pretty quick.

If your body is designed for marathon running, sure go for it. Those who are designed for endurance tend to have stronger tendons and simply have much more endurance muscle.

But for those who aren't, the idea is that they can still do lots of walking without getting into long running.

So should fast-twitch people do cardio?
Of course. Again, cardio is just any exercise that raises your heart rate. You you probably already do this. If you do a set of pushups and end up panting at the end, that is cardio. If you lift many sets in succession and are breathing heavily throughout, that is cardio--intense cardio.

Some people seem to be designed for high-intensity cardio, others for low-intensity cardio. That's fine, figure out what you are designed to do and do it.

But in either case, walking is still vital.

Walking *a lot* is key

Just today I was thinking ath

I personally have a sort of human odometer inside. My body senses when I am not moving i.e. sitting around all day. I have to walk literally around 4+ hours a day (ideally 5+) and be on my feet another 2 hours to feel right.

I had just had this thought, to try to walk 4 hours a day and stand another 2, then I looked up "walk four hours a day" and found an article saying the exact same thing.

Long, slow walks may beat shorter, high intensity runs
http://www.today.com/health/long-slow-walks-may-beat-shorter-higher-intensity-runs-1C8364882

Fatworks sells purified, grass-fed beef tallow (fat) for cooking

Fatworks is a company that sells purified, grass-fed beef tallow (fat) for cooking.

Beef tallow is a great source of saturated fat. It is marketed for paleo dieters... however, beef tallow has been a standard cooking oil ever since man has cooked food. You kill the animal, melt the fat and cook the meat in it.

Also beef tallow it is non-allergenic unlike many plant oils which have sterols that cause issues.

Fatworks, Inc.
http://fatworks.wazala.com/

Getting aluminum out of your body is one of the best and easiest things you can do

Humans do not need any aluminum in the body. Aluminum is a neurotoxin, a poison for humans. Yet millions of people have astoundingly high aluminum levels due to our can-centered food system.

Getting aluminum out of your body is one of the best things you can do for health. Removing aluminum is easy in principle, but only shows big results with long term persistence because it is gradual. If you do this chelation below for six months or a year, you will make huge strides in lowering your aluminum. You may feel a little worse when you do a chelation cycle (below) because aluminum is being pulled out into the bloodstream from wherever it has settled, but overall you will feel a lot better at the end of the cycle.

How to get aluminum out of your body

What to do: Take Magnesium Malate in little bits (ex. 200-300 mg) througout the day. This binds to aluminum and you urinate it out. Bite off just a piece of a larger tablet every couple hours, going through a couple tablets a day. Spacing it out like this is much more effective.

It is best to do this in cycles, like 4 days on, 4 off, especially depending on how high your aluminum levels are. Play around to see what your body can tolerate.

Malic acid is the active ingredient that binds to (chelates) aluminum. The best form is Magnesium Malate a combination of magnesium and malic acid.

*Key point*: do not take a ton of magnesium malate at once--you will feel terrible, especially if you have high aluminum levels. This is because high amounts of magnesium malate will pull much more aluminum into your bloodstream than your body can clear out, so you will have high blood aluminum that has to resettle in the body.

It is much more effective to use continous little bits (like 200-300 mg) of magnesium malate every 3-4 hours to allow aluminum to clear from your bloodstream at an even rate.

How it works: Like a magnet which attracts iron filings, magnesium malate attracts and binds to aluminum. This general binding process is called chelation.