Toward the end, good ideas for boosting SIRT1 through training
New Ideas About Nutrition and the Adaptation to Endurance Training
http://www.gssiweb.org/Article/sse-115-new-ideas-about-nutrition-and-the-adaptation-to-endurance-training
"a) Once or twice a week, start an 'adaptive' session in a caloric deficit (i.e., in a fasted state such as in the morning before breakfast). This will make sure that SIRT1 activity would be high.
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d) Train at a low absolute intensity for a long time to maximize the amount of time all of these signals are on while minimizing the mechanical strain on our bodies.
e) Alternatively, use double sessions where the first session depletes glycogen and the second session is performed at a high intensity in a glycogen-depleted state."